Table 1.

Histologic and clinical characteristics of baseline biopsies

Non-dys (%)LGD (%)HGD (%)P
Lung cancer statusa
 Cancer negative598 (59.0)179 (17.7)237 (23.4)<0.001
 Prevalent lung cancer34 (46.6)8 (11.0)31 (42.5)
 Incident lung cancer33 (42.9)14 (18.2)30 (40.0)
Lung cancer subtypeb
 Cancer negative598 (58.7)179 (17.8)237 (23.5)<0.001
 SCC positive34 (37.6)19 (16.8)53 (45.5)
 Adenocarcinoma positive16 (85.0)1 (5.0)2 (10.0)
Tobacco status
 Current smoker231 (42.8)138 (25.6)171 (31.7)<0.001
 Former smoker423 (68.9)66 (10.8)125 (20.4)
 Never smoker13 (81.3)0 (0.0)3 (18.8)
Tobacco—pack years
 Never smoker13 (81.3)0 (0.0)3 (18.8)<0.001
 0–40 pack years273 (64.8)73 (17.3)75 (17.8)
 40–72 pack years238 (48.7)107 (21.9)144 (29.4)
 >72 pack years143 (58.6)24 (9.8)77 (31.6)
Gender
 Male478 (54.9)162 (18.6)231 (26.5)0.0369
 Female189 (63.2)42 (14.1)68 (22.7)
Age
 <55 y.o.189 (59.1)66 (20.6)65 (20.3)0.0079
 55–65 y.o.259 (52.6)88 (17.9)145 (29.5)
 >65 y.o.219 (61.2)50 (14.0)89 (24.8)

NOTE: Correlation between baseline histology and clinical variables.

  • aCancer status unknown for 6 sites.

  • bCancer subtype unknown for 31 sites.