Table 1.

Cytotoxic activity of PFPE on normal breast and breast cancer cell lines

Parameters
Cell linesIC50 value ± SD (μg/mL)aSIb
MCF-77.45 ± 0.606.22, 4.54
MDA-MB-46818.19 ± 0.592.55, 1.86
MDA-MB-23122.67 ± 2.312.04, 1.49
ZR-75-113.85 ± 1.253.34, 2.44
MCF-12A46.31 ± 0.76c
HT-2927.74 ± 0.911.66, 1.22
SW-62029.56 ± 2.471.57, 1.14
H-35834.69 ± 3.051.33, 0.97
A-54930.77 ± 1.231.51, 1.09
LA-N-5111.28 ± 8.850.42, 0.30
SK-N-SH21.51 ± 1.522.15, 1.57
L-92933.82 ± 1.12c
  • aThe value obtained from three independent experiments.

  • bSI value = (IC50 values of MCF-12A/IC50 value of cancer call lines, IC50 values of L-929/IC50 value of cancer call lines).

  • cNot tested.