Table 1.

Characteristics of women referred to an image-guided breast biopsy and diagnosed with benign breast disease, The BREAST Stamp Project, 2007–2010

PremenopausalPostmenopausal
Characteristic (n = 348 women)n (%)n (%)
Age at mammogram (years)
 39–4474 (32.7)1 (0.8)
 45–4994 (41.6)5 (4.1)
 50–5455 (24.3)29 (23.8)
 55–593 (1.3)47 (38.5)
 60–650 (0.0)40 (32.8)
White, non-Hispanic race213 (94.2)110 (90.2)
College/graduate school degree197 (87.2)95 (77.9)
BMI, kg/m2
 <25112 (49.6)48 (39.3)
 25–<3064 (28.3)35 (28.7)
 30+50 (22.1)39 (32.0)
Age at menarche (years)
 ≤1283 (36.7)46 (37.7)
 1386 (38.1)41 (33.6)
 ≥1454 (23.9)32 (26.2)
Parity
 Nulliparous57 (25.2)30 (24.6)
 122 (9.7)23 (18.9)
 294 (41.6)43 (35.2)
 3+53 (23.5)26 (21.3)
Age at first birth (years)
 <2556 (33.1)54 (58.7)
 25–<3056 (33.1)22 (23.9)
 30+57 (33.7)15 (16.3)
Menopausal hormone therapy use
 Never194 (85.8)69 (56.6)
 Former22 (9.7)33 (27.0)
 Current3 (1.3)15 (12.3)
Cigarette smoking, 100+ cigarettes/lifetime
 Never125 (55.3)51 (41.8)
 Former72 (31.9)47 (38.5)
 Current19 (8.4)16 (13.1)
Breast biopsy prior to enrollment69 (30.5)49 (40.2)
Family history of breast cancer in a first-degree female relative52 (23.0)29 (23.8)
Biopsy type
 Ultrasound-guided119 (52.7)49 (40.2)
 Stereotactic-guided102 (45.1)71 (58.2)
 Both5 (2.2)2 (1.6)
Biopsy laterality and number
 Left
  One biopsy101 (44.7)44 (36.1)
  Two biopsies11 (4.9)7 (5.7)
 Right
  One biopsy96 (42.5)60 (49.2)
  Two biopsies11 (4.9)8 (6.6)
 Bilateral biopsies7 (3.1)3 (2.5)
Pathologic diagnosisa
 Benign95 (42.0)48 (39.3)
 Proliferative113 (50.0)58 (47.5)
 Proliferative with atypiab18 (8.0)16 (13.1)
Characteristic (per biopsy target, n = 395 biopsies)
Biopsy type
 Ultrasound-guided140 (54.9)53 (37.9)
 Stereotactic-guided115 (45.1)87 (62.1)
Pathologic diagnosis
 Benign111 (43.5)56 (40.0)
 Proliferative125 (49.0)66 (47.1)
 Proliferative with atypiac19 (7.5)18 (12.9)

NOTE: Missing values were excluded from percentage calculations.

  • aAmong women with multiple biopsies, this was the worst pathologic diagnosis.

  • bIncludes n = 9 atypical ductal, n = 7 atypical lobular hyperplasia, and n = 2 with both diagnoses among premenopausal women, and n = 6 atypical ductal hyperplasia and n = 10 atypical lobular hyperplasia diagnoses among postmenopausal women.

  • cIncludes n = 9 atypical ductal, n = 8 atypical lobular hyperplasia, and n = 2 with both diagnoses among premenopausal women, and n = 7 atypical ductal and n = 11 atypical lobular hyperplasia diagnoses among postmenopausal women.