Table 4.

Hematologic values and clinical chemistry values of the study of anticancer activity on induced mammary tumorigenesis in rats

PFPE
NormalControlVehicle100 mg/kg200 mg/kg400 mg/kg
Hematologic values
 White blood cells (×103/μL)2.90 ± 0.813.15 ± 1.714.28 ± 1.975.35 ± 2.943.17 ± 0.956.51 ± 3.79
 Neutrophil (%)85.25 ± 4.8373.13 ± 12.1767.90 ± 14.3277.70 ± 11.5074.78 ± 10.6675.71 ± 7.09
 Lymphocyte (%)14.75 ± 4.8325.75 ± 11.9429.30 ± 12.8921.50 ± 11.2723.33 ± 8.8023.29 ± 6.53
 Monocyte (%)0.00 ± 0.000.50 ± 1.072.50 ± 2.370.30 ± 0.480.78 ± 0.971.00 ± 1.82
 Eosinophil (%)0.00 ± 0.000.62 ± 0.920.30 ± 0.480.50 ± 0.851.11 ± 1.360.00 ± 0.00
 Basophil (%)0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
 Red blood cells (×106/μL)6.82 ± 0.366.29 ± 0.505.99 ± 1.236.47 ± 1.306.67 ± 1.265.38 ± 1.95
 Hemoglobin g/dl)13.79 ± 0.5113.60 ± 0.9012.63 ± 2.1613.49 ± 2.6513.81 ± 2.5211.77 ± 3.72
 Hematocrit (%)38.53 ± 1.7436.21 ± 3.0535.31 ± 5.7038.30 ± 7.7138.94 ± 6.8932.83 ± 9.88
 Mean corpuscular volume (fl)56.55 ± 1.0459.35 ± 2.6259.71 ± 5.9758.15 ± 1.0858.52 ± 1.9864.46 ± 11.44
 Mean corpuscular hemoglobin (pg)20.25 ± 0.6121.45 ± 0.6921.29 ± 1.7420.62 ± 0.6720.76. ± 0.8822.83 ± 3.19
 Mean corpuscular hemoglobin concentration (g/dl)35.82 ± 0.7836.78 ± 1.0935.71 ± 1.0735.47 ± 0.8735.42 ± 1.0235.59 ± 1.84
 Platelet (×105/μL)546.75 ± 59.88512.63 ± 96.94522.90 ± 107.51440.20 ± 79.52508.89 ± 172.14520.02 ± 112.47
Clinical blood chemistry values
 BUN (mg/dl)22.93 ± 3.7632.04 ± 10.0425.49 ± 2.8825.31 ± 6.8121.47 ± 2.8228.21 ± 4.95
 Creatinine (mg/dl)0.57 ± 0.130.52 ± 0.130.52 ± 0.100.48 ± 0.050.47 ± 0.070.50 ± 0.14
 Total protein (g/dl)6.77 ± 0.475.57 ± 0.365.78 ± 0.626.04 ± 0.506.29 ± 0.265.82 ± 0.79
 Albumin (g/dl)3.42 ± 0.203.11 ± 0.243.24 ± 0.183.21 ± 0.283.48 ± 0.163.11 ± 0.31
 Total bilirubin (mg/dl)0.20 ± 0.110.33 ± 0.140.27 ± 0.050.28 ± 0.060.39 ± 0.140.32 ± 0.14
 SGOT (U/L)109.83 ± 21.14179.38 ± 31.56136.89 ± 26.11125.20 ± 34.74127.89 ± 71.51137.86 ± 34.29
 SGPT (U/L)55.00 ± 17.7256.38 ± 11.3556.89 ± 11.9246.57 ± 9.9555.00 ± 14.3454.71 ± 12.72
 Alkaline phosphatase (U/L)82.33 ± 20.42123.88 ± 30.12136.22 ± 27.23105.00 ± 47.5888.00 ± 12.02118.86 ± 38.05

Abbreviations: SGOT, serum glutamic oxaloacetic transaminase; SGPT, serum glutamic pyruvic transaminase.