Table 3.

Age-adjusted Spearman correlation coefficient between plasma biomarkers and lifestyle factors among control participants in the Nurses' Health Study (1990)

Total 25(OH)DVDBPFree 25(OH)DBioavailable 25(OH)DVDBP-bound 25(OH)DAlbuminCRPsTNFR-2IL6MIC-1BMIMETs-hours/weekPack-years of smoking
Total 25(OH)D10.090.60a0.58a0.98a−0.02−0.0060.10c−0.070.04−0.12c0.16b0.06
VDBP1−0.58a−0.57a0.23a0.040.030.11c0.020.06−0.06−0.020.03
Free 25(OH)D10.99a0.45a−0.02−0.030.03−0.090.02−0.020.12c0.02
Bioavailable 25(OH)D10.44a0.11c−0.05−0.007−0.11c0.009−0.040.11c0.03
VDBP-bound 25(OH)D1−0.030.0080.11c−0.060.04−0.12c0.14b0.06
Albumin1−0.23a−0.19a−0.19a0.003−0.20a0.040.009
CRP10.27a0.48a0.15b0.40a−0.15b0.02
sTNFR-210.19a0.34a0.28a−0.07−0.04
IL610.22a0.26a−0.100.10c
MIC-11−0.01−0.080.22a
BMI1−0.16b−0.04
METs-hours/week1−0.10
Pack-years of smoking1
  • Abbreviation: MET, metabolic equivalent.

  • aP < 0.001.

  • bP < 0.01.

  • cP < 0.05.