Table 3.

Risk of advanced stage prostate cancer—pT3 and higher—(ORs and 95% CIs) by quartile of dietary intake among 971 men in the Washington University Genetics Study

Quartile of intake
Q1Q2Q3Q4Ptrend
Total red meat, median, g/d3970109180
 N events/N participants50/24254/24348/24357/243
 Age-adjusted1.001.14 (0.74–1.77)1.02 (0.64–1.62)1.30 (0.78–2.16)0.38
 Covariate-adjusted1.001.10 (0.70–1.73)0.99 (0.61–1.62)1.23 (0.71–2.14)0.51
Unproc red meat (Median)265283142
 N events/N participants44/24258/24354/24353/243
 Age-adjusted1.001.44 (0.93–2.24)1.38 (0.87–2.20)1.35 (0.81–2.25)0.40
 Covariate-adjusted1.001.36 (0.86–2.15)1.31 (0.81–2.13)1.25 (0.73–2.15)0.60
Processed meat (Median)381736
 N events/N participants50/24254/24354/24351/243
 Age-adjusted1.001.09 (0.71–1.69)1.08 (0.70–1.68)1.02 (0.64–1.62)0.95
 Covariate-adjusted1.000.97 (0.61–1.53)1.10 (0.69–1.75)0.96 (0.58–1.58)0.91
Rare/Medium rare red meat0102761
 N events/N participants45/24757/22157/26850/235
 Age-adjusted1.001.58 (1.01–2.47)1.18 (0.75–1.84)1.11 (0.66–1.87)0.92
 Covariate-adjusted1.001.60 (1.01–2.55)1.14 (0.72–1.81)1.06 (0.61–1.84)0.76
Well/Very well-done red meat391845
 N events/N participants42/24346/24257/24264/244
 Age-adjusted1.001.12 (0.70–1.80)1.48 (0.94–2.34)1.71 (1.05–2.79)0.02
 Covariate-adjusted1.001.00 (0.61–1.63)1.34 (0.83–2.15)1.74 (1.05–2.90)0.01
Poultry (Median)5132349
 N events/N participants51/23256/25053/23949/250
 Age-adjusted1.001.02 (0.66–1.57)1.05 (0.67–1.65)0.89 (0.56–1.42)0.56
 Covariate-adjusted1.001.08 (0.69–1.68)1.08 (0.68–1.72)0.94 (0.57–1.53)0.67
Fried Poultry01612
 N events/N participants25/12181/36338/22665/261
 Age-adjusted1.001.09 (0.66–1.81)0.77 (0.44–1.35)1.26 (0.74–2.15)0.43
 Covariate-adjusted1.001.14 (0.68–1.93)0.72 (0.40–1.29)1.29 (0.73–2.26)0.47
Not fried poultry161135
 N events/N participants34/15369/32739/17267/319
 Age-adjusted1.000.96 (0.60–1.54)1.08 (0.64–1.83)0.99 (0.61–1.60)0.97
 Covariate-adjusted1.000.98 (0.60–1.61)1.09 (0.62–1.90)1.06 (0.63–1.77)0.79
Fish (Median)5132550
 N events/N participants55/23651/24859/24344/244
 Age-adjusted1.000.85 (0.55–1.30)1.04 (0.68–1.58)0.70 (0.44–1.10)0.17
 Covariate-adjusted1.000.92 (0.59–1.45)1.04 (0.67–1.63)0.64 (0.40–1.03)0.07
Fried fish02517
 N events/N participants42/18635/19473/33259/259
 Age-adjusted1.000.73 (0.44–1.20)0.93 (0.60–1.44)0.96 (0.60–1.52)0.69
 Covariate-adjusted1.000.68 (0.40–1.16)0.91 (0.58–1.44)0.87 (0.53–1.41)0.98
Not fried fish02416
 N events/N participants47/19634/17844/22284/375
 Age-adjusted1.000.75 (0.45–1.23)0.80 (0.50–1.28)0.92 (0.61–1.39)0.71
 Covariate-adjusted1.000.73 (0.43–1.23)0.77 (0.47–1.26)0.94 (0.60–1.46)0.58
Eggs (Median)371239
 N events/N participants32/17536/19854/24187/357
 Age-adjusted1.001.01 (0.59–1.71)1.34 (0.81–2.19)1.45 (0.91–2.32)0.08
 Covariate-adjusted1.000.92 (0.53–1.59)1.23 (0.74–2.05)1.32 (0.81–2.14)0.16
  • NOTE: Age-adjusted models adjusted for age at diagnosis and total energy intake. Covariate adjusted models additionally adjusted for: race, family history of prostate cancer, BMI (5 categories), smoking (never/former/current), vigorous physical activity (6 categories), total calcium intake (quartiles), cooked tomato products intake (quartiles), coffee intake (5 categories), and clinical stage (T1, T2). Models for red meat by doneness also adjust for total red meat intake.