Table 2.

Demographic characteristics of REDUCE participants according to statin use

Statin use
No N = 5,438 (82%)Yes N = 1,217 (18%)P
Age, mean (SD), y62.6 (6.0)63.1 (6.1)0.005
Race, n (%)
 White4,964 (91)1,134 (93)0.031
 Non-white474 (9)83 (7)
Region, n (%)
 North America1,274 (23)624 (51)<0.0001
 Europe3,398 (62)539 (44)
 Other766 (14)54 (4)
BMI, median (IQR), kg/m226.8 (24.7–29.1)27.4 (25.4–30.1)0.0001
Diabetes, n (%)
 No5,063 (93)1,032 (85)<0.0001
 Yes375 (7)185 (15)
NSAID use, n (%)
 No4,207 (77)497 (41)<0.0001
 Yes1,231 (23)720 (59)
Alcohol use, n (%)a
 None1,383 (26)349 (29)0.054
 Moderate2,630 (49)553 (46)
 Heavy1,400 (26)309 (26)
Smoking status, n (%)
 Never2,546 (47)473 (39)<0.0001
 Former2,052 (38)580 (48)
 Current840 (15)164 (13)
  • Abbreviation: IQR, interquartile range.

  • aData for alcohol use was missing for n = 31 participants.