Table 5.

ORs for associations between statin use and presence and extent of baseline prostate inflammation in REDUCE

Presence of chronic inflammationExtent of chronic inflammation
NoneAnyNoneModerate; <20% of coresSevere; ≥20% of cores
nnOR (95% CI)nnOR (95% CI)nOR (95% CI)
Statin use
 No1,2124,22611,2121,59212,5821
 Yes2929250.81 (0.69–0.95)2923460.82 (0.68–0.99)5700.80 (0.68–0.95)
Presence of acute inflammationExtent of acute inflammation
NoneAnyNoneModerate; <20% of coresSevere; ≥20% of cores
nnOR (95% CI)nnOR (95% CI)nOR (95% CI)
Statin use
 No4,63280614,63253012691
 Yes1,0181990.97 (0.81–1.17)1,0181431.11 (0.90–1.38)540.73 (0.53–1.00)
  • NOTE: ORs were adjusted for age at baseline (continuous), race (white, non-white), geographic region (North America, Europe, other), BMI (continuous, log-transformed), smoking status (never, former, current), and NSAID use (yes, no).