Table 2.

Gene methylation prevalence over time in sputum

Baseline6-Month12-Month24-Month48-Month
Genen (%)n (%)n (%)n (%)n (%)
CDKN2507 (35)313 (42)220 (39)154 (45)75 (49)
MGMT504 (43)313 (42)223 (47)154 (49)75 (53)
RASSF1509 (10)313 (4)223 (4)154 (0)75 (3)
DAPK1502 (43)307 (42)223 (46)154 (36)75 (31)
GATA4505 (71)309 (75)222 (84)153 (78)75 (85)
GATA5505 (45)311 (51)222 (52)153 (51)75 (45)
PAX5α504 (31)312 (35)223 (32)154 (29)75 (45)
PAX5β507 (31)313 (41)222 (39)154 (44)75 (53)
  • NOTE: Minor sample size differences across genes reflect the lack of detection of an unmethylated or methylated gene product, thus leading to unknown status.