Table 3.

Baseline characteristics of unmatched and propensity score–matched patients in NSAID user and nonuser groups

UnmatchedPropensity score matched
NSAIDs usen = 898 (%)Nonusen = 49,211 (%)PNSAID usen = 898 (%)Nonusen = 898 (%)P
Age, years
 <50161 (17.93)10,212 (20.75)<0.001161 (17.93)146 (16.26)0.534
 50—60179 (19.33)9,607 (19.52)179 (19.93)160 (17.82)
 60—70304 (33.85)14,106 (28.66)304 (33.85)331 (36.86)
 70—80228 (25.39)11,642 (23.66)228 (25.39)232 (25.84)
 ≥8026 (2.90)3,644 (7.40)26 (2.90)29 (3.23)
Sex, male449 (50.00)28,006 (56.91)<0.001449 (50.00)445 (49.55)0.850
Comorbidities
 Ischemic heart disease227 (25.28)5,625 (11.43)<0.001227 (25.28)249 (27.73)0.240
 Chronic heart failure319 (35.52)6,998 (14.22)<0.001319 (35.52)325 (36.19)0.768
 Peripheral vascular disease111 (12.36)2,311 (4.70)<0.001111 (12.36)103 (11.47)0.560
 Cerebrovascular disease130 (14.48)2,571 (5.22)<0.001130 (14.48)128 (14.25)0.893
 Dementia36 (4.01)844 (1.72)<0.00136 (4.01)30 (3.34)0.452
 COPD58 (6.46)1,093 (2.22)<0.00158 (6.46)60 (6.68)0.850
 Collagen diseases198 (22.05)2,686 (5.46)<0.001198 (22.05)190 (21.16)0.647
 Peptic ulcers625 (69.60)14,112 (28.68)<0.001625 (69.60)627 (69.82)0.918
 Diabetes568 (62.35)14,046 (28.54)<0.001568 (63.25)573 (63.81)0.806
 Chronic kidney disease30 (3.34)1,407 (2.86)0.39130 (3.34)24 (2.67)0.407
 Hemiplegia or paraplegia63 (7.02)1,164 (2.37)<0.00163 (7.02)63 (7.02)1.000
 Leukemia13 (1.45)394 (0.80)0.03213 (1.45)12 (1.34)0.840
 Malignant lymphoma82 (9.13)1,340 (2.72)<0.00182 (9.13)81 (9.02)0.935
 Liver cirrhosis98 (10.91)2,253 (4.58)<0.00198 (10.91)93 (10.36)0.702
 AIDS3 (0.33)79 (0.16)0.2023 (0.33)2 (0.22)1.000
H. pylori infection status
 Negative169 (18.82)1,557 (3.16)<0.001169 (18.82)172 (19.15)0.981
 Positive667 (74.28)5,768 (11.72)667 (74.28)665 (74.05)
 Unknown62 (6.90)41,886 (85.12)62 (6.90)61 (6.79)
  • NOTE: Bold indicates statistical significance (P < 0.05).

  • Abbreviations: AIDS, acquired immunodeficiency syndrome; COPD, chronic obstructive pulmonary disease.