Table 2.

Small molecules that downregulate Sp transcription factors in cancer cells

References
1.Natural products and synthetic analogues:(14, 15, 18–22, 25, 26, 39, 70, 74, 81, 85–92)
PEITC, BITC, celastrol, curcumin, betulinic acid, resveratrol, polyphenolics, bardoxolone-Me (CDDO-Me), CDODA-Me, isorhapontigenin, triptolide, β-lapachone, honokiol, piperlongumine
2.NSAIDs:(16, 17, 67, 68, 83)
Aspirin, tolfenamic acid, celecoxib, GT-094, diclofenac, salicylate
3.Other drugs:(23, 24, 66, 75–80)
Metformin, HDAC inhibitors, retinoids, α-tocopherol, thiazolidinediones, proteasome inhibitors
4.Other compounds:(70–73, 82, 84, 93)
Arsenic trioxide, ascorbic acid, t-butyl hydroperoxide, hydrogen peroxide, zinc depletion, WIN 55,212-12, penfluridol