Table 3.

Change in biomarkers

ControlIntervention
VariableBaseline (mean ± SD)Final (mean ± SD)Change (LSM ± SE)Baseline (mean ± SD)Final (mean ± SD)Change (LSM ± SE)P value
Insulin (μIU/mL)12.28 ± 3.5612.80 ± 5.020.52 ± 1.0510.64 ± 4.198.76 ± 3.14−1.88 ± 0.980.03
IL1β (pg/mL)0.13 ± 0.060.09 ± 0.04−0.04 ± 0.110.25 ± 0.620.11 ± 0.04−0.14 ± 0.100.43
IL6 (pg/mL)1.43 ± 1.591.36 ± 1.01−0.06 ± 0.271.01 ± 0.900.78 ± 0.57−0.24 ± 0.250.09
IL8 (pg/mL)5.34 ± 1.964.56 ± 1.20a−0.78 ± 0.385.08 ± 1.075.07 ± 1.490.07 ± 0.360.15
TNFα (pg/mL)2.18 ± 0.522.08 ± 0.43−0.11 ± 0.132.40 ± 1.182.16 ± 0.85a−0.30 ± 0.120.49
  • Values are presented as mean ± SD and least squares mean (LSM) ± SEM.

  • aP < 0.05 within group, P-value baseline adjusted linear regression model.