Table 3.

Incidence rates of colon cancer by deciles of predicted risk

Model with categorized variablesModel with continuous variables
Risk decileCasesPerson-yearsIncidence rate (per 105)Incidence rate ratio (95% CI)CasesPerson-yearsIncidence rate (per 105)Incidence rate ratio (95% CI)
Women in the NHS
1 (lowest)69106,642651.00 (reference)65108,870601.00 (reference)
232132,504240.37 (0.25–0.57)35131,114270.45 (0.30–0.67)
359131,621450.69 (0.49–0.98)51131,581390.65 (0.45–0.94)
468128,896530.82 (0.58–1.14)77129,050601.00 (0.72–1.39)
585127,057671.03 (0.75–1.42)84127,739661.10 (0.80–1.52)
683126,052661.02 (0.74–1.40)80125,885641.06 (0.77–1.48)
7108126,536851.32 (0.98–1.78)99127,195781.30 (0.95–1.78)
898128,819761.18 (0.86–1.60)103127,900811.35 (0.99–1.84)
996131,189731.13 (0.83–1.54)106130,848811.36 (1.00–1.85)
10 (highest)118131,190901.39 (1.03–1.87)116130,326891.49 (1.10–2.02)
Men in the HPFS
1 (lowest)2042,107481.00 (reference)2042,378471.00 (reference)
22065,249310.65 (0.35–1.20)2066,776300.63 (0.34–1.18)
32768,175400.83 (0.47–1.49)2668,132380.81 (0.45–1.45)
43167,105460.97 (0.55–1.71)3266,669481.02 (0.58–1.78)
54765,543721.51 (0.89–2.55)4265,320641.36 (0.80–2.32)
63863,808601.25 (0.73–2.15)4263,641661.40 (0.82–2.38)
74460,793721.52 (0.90–2.59)4361,101701.49 (0.88–2.53)
83959,150661.39 (0.81–2.38)3858,690651.37 (0.80–2.36)
94756,628831.75 (1.04–2.95)5856,0411042.19 (1.32–3.65)
10 (highest)9949,6022004.20 (2.60–6.79)9149,4111843.90 (2.41–6.33)