Table 4.

Multivariate-adjusted HR of subtypes of bladder cancers in relation to smoking status

Numbers of casesMulti-adjusted HR (95% CI)a
VariableTransitionalPapillaryOther typesbTransitionalPapillaryOther typesb
Never smoker (ref)57220431.001.001.00
Former smoker (years since quitting smoking)66282902.35 (1.56–3.54)2.42 (1.99–2.94)3.57 (1.86–6.87)
 <101557212.98 (1.66–5.34)2.65 (2.00–3.52)4.71 (2.69–8.23)
 10–<202177321.86 (1.05–3.31)2.33 (1.80–3.02)4.94 (2.72–7.11)
 20–<301582172.95 (1.73–5.05)2.53 (1.92–3.34)2.04 (1.06–3.93)
 ≥301566201.88 (0.94–3.76)1.87 (1.31–2.67)2.22 (1.11–4.44)
Current smoker1682143.66 (1.96–6.82)3.91 (2.96–5.17)5.45 (2.60–11.46)
  • aAdjusted for age, education, race/ethnicity, occupation, marital status alcohol consumption, physical activity, family history of cancer, BMI, daily total energy intake and percentage of energy from fat, daily fruit consumption and daily vegetable consumption, and pack-years.

  • bIncluding squamous cell carcinoma, adenocarcinoma, and other types, which include adenocarcinoma, squamous cell carcinoma, small cell carcinoma, lymphoepithelial carcinoma, hemangiosarcoma, clear cell adenocarcinoma, and undifferentiated carcinoma.