Table 2.

Pancreatic abnormalities identified in HRIs testing positive or negative for BRCA mutations

BRCA positive
Total (48; n, %)BRCA1 (18; n, %)BRCA2 (30; n, %)BRCA negative (35; n, %)
Any abnormality on MRCP/CT16 (33)13 (37)
Abnormality identified as IPMN15 (31)6 (33)9 (30)12 (34)
 Prevalent (found on first MRCP/CT)11 (23)5 (28)6 (20)10 (29)
 Incident (found on subsequent MRCP/CT)4 (8)1 (6)3 (10)2 (6)
  • NOTE: Abnormalities other than branch-duct IPMNs were 1 BRCA-positive patient with chronic pancreatitis and 1 BRCA-negative patient with metastatic serous carcinoma of mullerian origin to pancreas.