Table 2.

Adenoma detection by study arm

Colonoscopy at 1 year (all patients)Colonoscopy at 1 year (nonaspirin users)First poststudy colonoscopy (all patients)d
DFMO + aspirin (n = 42)Double placebo (n = 44)Total (n = 86)PaDFMO + aspirin (n = 28)Double placebo (n = 29)Total (n = 57)PDFMO + aspirin (n = 20)Double placebo (n = 18)Total (n = 38)P
Any adenoma n (%)16 (38.1)18 (40.9)34 (39.5)0.7896a8 (28.6)13 (44.8)21 (36.8)0.2034a10 (50)10 (55.6)20 (52.6)0.7568b
Adenoma ≥ 5 mm, n (%)5 (11.9)5 (11.4)10 (11.6)1.0000b3 (10.3)3 (10.0)6 (10.2)1.0000b5 (25)7 (38.9)12 (31.6)0.4889b
Advanced adenomas, n (%)3 (7.1)3 (6.8)6 (7)1.0000b3 (10.3)3 (10.0)6 (10.2)1.0000b2 (10)2 (11.1)4 (10.5)1.0000b
Multiple adenomas, n (%)7 (16.7)12 (27.9)419 (22.4)0.2136a5 (17.9)10 (35.7)c15 (26.8)0.1314a0000
  • aχ2 P value.

  • bFisher exact P value.

  • cMissing data; double placebo arm (n = 1).

  • dMedian interval of 35 months post end-of-study colonoscopy.