Table 1.

Clinical characteristics of participants.

PlaceboBerberine
Number412
Age, mean (range)49 (33–55)45 (24–63)
Gender
 Female, number (%)2 (50)6 (50)
 Male, number (%)2 (50)6 (50)
BMI, mean (range)22.7 (18.1–27.1)22.3 (16.3–25)
UCDAI score
 002
 1410
ECOG performance status, mean (range)0 (0,0)0 (0,0)
Duration of ulcerative colitis (years), mean (range)9.5 (1.6–20.8)3.0 (0.5–5.8)
Baseline symptoms and history, patient reported
 Nonea310
 Suspected cholangitis in the past10
 Hypertension01
 Abdominal distension, epigastric discomfort01
  • Abbreviation: BMI, body mass index.

  • aDoes not include changes in stool.