Table 3.

Comparison of epidemiologic risk factors in female patients with Barrett's esophagus (n = 151) and female population–based controls (n = 1,028).

Barrett cohortPopulation-based control
Characteristicsn (%)n (%)P
Total1511,028
Age (years)
 Mean (SD)64.4 (12.9)59.0 (12.0)<0.001
 Range27–9338–88
GERD symptoms
 Yes99 (65.6)511 (49.7)<0.001
 No42 (27.8)517 (50.3)
 Missing10 (6.6)
GERD frequency among those answering yes to symptoms
 Frequently54 (54.6)135 (26.4)<0.001
 Occasionally33 (33.3)376 (73.6)
 Missing12 (12.1)
Reasons for Barrett's esophagus diagnosis
 Dysphagia13 (8.6)
 Reflux52 (34.4)
 Upper abdominal discomfort20 (13.2)
 Incidental finding33 (21.9)
 Other11 (7.3)
 Missing22 (14.6)
Smoking
 Regular smoker19 (12.6)126 (12.3)0.133
 Irregular smoker8 (5.3)25 (2.4)
 Ex-smoker46 (30.4)329 (32)
 Nonsmoker67 (44.4)548 (53.3)
 Missing11 (7.3)
Alcohol consumption
 <40 g/day112 (74.2)986 (95.9)0.748
 >40 g/day6 (4.0)41 (4)
 Missing33 (21.8)1 (0.1)
BMI (kg/m2)
 Mean BMI (SD)26.9 (6.6)27.4 (5.5)0.103
 Range16.7–70.616.6–48.8
 Missing8
Marital status
 Married82 (54.3)706 (68.7)0.047
 Single19 (12.6)99 (9.6)
 Divorced19 (12.6)94 (9.1)
 Widowed24 (15.9)129 (12.6)
 Missing7 (4.6)
Physical activity
 Very active33 (21.9)254 (24.7)0.446
 Moderately active44 (29.1)363 (35.3)
 Little active16 (10.6)149 (14.5)
 Not active43 (28.5)262 (25.5)
 Missing15 (9.9)
Actual state of fitness
 Very good9 (6.0)132 (12.8)<0.001
 Good75 (49.7)670 (65.2)
 Intermediate53 (35.1)206 (20)
 Poor5 (3.3)20 (2)
 Missing9 (5.9)
Relative state of health
 Better32 (21.2)408 (39.7)<0.001
 Equal31 (20.5)89 (8.6)
 Worse53 (35.1)513 (49.9)
 Unknown27 (17.9)18 (1.8)
 Missing8 (5.3)
Chronic diseases
 Diabetes18 (11.9)71 (6.9)0.044
 Hypertension76 (50.3)473 (46)0.365
 Hypercholesterolemia70 (46.4)487 (47.4)0.884
 Neurodermatitis12 (7.9)84 (8.2)1
 Asthma19 (12.6)97 (9.4)0.286
 Hay fever25 (16.6)205 (19.9)0.384
  • Note: P values are from Wilcoxon and χ2 tests.