Table 1.

Patient demographics for analysis cohorts.

Demographic featuresAll enrolled participants, N = 983Intent-to-screen cohorta, N = 842Evaluable cohortb,N = 816
Age (years)
 Mean (SD)47.8 (1.5)47.9 (1.5)47.8 (1.5)
Sex, n (%)
 Male518 (52.7%)440 (52.3%)427 (52.3%)
 Female465 (47.3%)402 (47.7%)389 (47.7%)
Race, n (%)
 White803 (81.7%)706 (83.8%)685 (83.9%)
 Black or African American127 (12.9%)95 (11.3%)90 (11.0%)
 Asian41 (4.2%)31 (3.7%)31 (3.8%)
 American Indian or Alaska Native1 (0.1%)1 (0.1%)1 (0.1%)
 Native Hawaiian or Other Pacific Islander1 (0.1%)1 (0.1%)1 (0.1%)
 Other10 (1.0%)8 (1.0%)8 (1.0%)
Ethnicity, n (%)
 Hispanic or Latino67 (6.8%)48 (5.7%)47 (5.8%)
 Not Hispanic or Latino916 (93.2%)794 (4.3%)769 (94.2%)
  • aThe intent-to-screen cohort included participants with a valid or usable mt-sDNA and a reportable or complete colonoscopy.

  • bThe evaluable cohort included only participants with a usable mt-sDNA and complete colonoscopy. Participants with stool samples received outside of the 72-hour mt-sDNA processing window, incomplete/not reportable colonoscopies, and other major protocol violations (inclusion/exclusion criteria not met) were excluded.